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Muc5ac Expression Protects the Colonic Barrier in Experimental Colitis

BACKGROUND: The mucus gel layer (MGL) lining the colon is integral to exclusion of bacteria and maintaining intestinal homeostasis in health and disease. Some MGL defects allowing bacteria to directly contact the colonic surface are commonly observed in ulcerative colitis (UC). The major macromolecu...

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Detalles Bibliográficos
Autores principales: Olli, Kristine E, Rapp, Caroline, O’Connell, Lauren, Collins, Colm B, McNamee, Eoin N, Jensen, Owen, Jedlicka, Paul, Allison, Kristen C, Goldberg, Matthew S, Gerich, Mark E, Frank, Daniel N, Ir, Diana, Robertson, Charles E, Evans, Christopher M, Aherne, Carol M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7441107/
https://www.ncbi.nlm.nih.gov/pubmed/32385500
http://dx.doi.org/10.1093/ibd/izaa064