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Shedding of cancer susceptibility candidate 4 by the convertases PC7/furin unravels a novel secretory protein implicated in cancer progression

The proprotein convertases (PCs) are responsible for the maturation of precursor proteins, and are involved in multiple and critical biological processes. Over the past 30 years, the PCs have had great translational applications, but the physiological roles of PC7, the seventh member of the family,...

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Detalles Bibliográficos
Autores principales: Duval, Stéphanie, Abu-Thuraia, Afnan, Elkholi, Islam E., Chen, Rui, Seebun, Deeptee, Mayne, Janice, Côté, Jean-François, Figeys, Daniel, Seidah, Nabil G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7441151/
https://www.ncbi.nlm.nih.gov/pubmed/32820145
http://dx.doi.org/10.1038/s41419-020-02893-0