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Shedding of cancer susceptibility candidate 4 by the convertases PC7/furin unravels a novel secretory protein implicated in cancer progression
The proprotein convertases (PCs) are responsible for the maturation of precursor proteins, and are involved in multiple and critical biological processes. Over the past 30 years, the PCs have had great translational applications, but the physiological roles of PC7, the seventh member of the family,...
Autores principales: | Duval, Stéphanie, Abu-Thuraia, Afnan, Elkholi, Islam E., Chen, Rui, Seebun, Deeptee, Mayne, Janice, Côté, Jean-François, Figeys, Daniel, Seidah, Nabil G. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7441151/ https://www.ncbi.nlm.nih.gov/pubmed/32820145 http://dx.doi.org/10.1038/s41419-020-02893-0 |
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