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Peripheral serum metabolomic profiles inform central cognitive impairment

The incidence of Alzheimer's disease (AD) increases with age and is becoming a significant cause of worldwide morbidity and mortality. However, the metabolic perturbation behind the onset of AD remains unclear. In this study, we performed metabolite profiling in both brain (n = 109) and matchin...

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Detalles Bibliográficos
Autores principales: Wang, Jingye, Wei, Runmin, Xie, Guoxiang, Arnold, Matthias, Kueider-Paisley, Alexandra, Louie, Gregory, Mahmoudian Dehkordi, Siamak, Blach, Colette, Baillie, Rebecca, Han, Xianlin, De Jager, Philip L., Bennett, David A., Kaddurah-Daouk, Rima, Jia, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7441317/
https://www.ncbi.nlm.nih.gov/pubmed/32820198
http://dx.doi.org/10.1038/s41598-020-70703-w