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CNTF Prevents Development of Outer Retinal Neovascularization Through Upregulation of CxCl10

PURPOSE: Ciliary neurotrophic factor (CNTF) is a well-characterized neurotrophic factor currently in clinical trials for the treatment of macular telangiectasia type II. Our previous work showed that CNTF-induced STAT3 signaling is a potent inhibitor of pathologic preretinal neovascular tuft formati...

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Detalles Bibliográficos
Autores principales: Bucher, Felicitas, Aguilar, Edith, Marra, Kyle V., Rapp, Julian, Arnold, Jakob, Diaz-Aguilar, Sophia, Lange, Clemens, Agostini, Hansjürgen, Schlunck, Günther, Stahl, Andreas, Friedlander, Martin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Association for Research in Vision and Ophthalmology 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7441336/
https://www.ncbi.nlm.nih.gov/pubmed/32780864
http://dx.doi.org/10.1167/iovs.61.10.20