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Autophagy in the Aging and Experimental Ocular Hypertensive Mouse Model

PURPOSE: To investigate autophagy in the outflow pathway and ganglion cell layer in the aging and ocular hypertensive mouse. METHODS: Both 4-month-old and 18-month-old C57BL/6J and GFP-LC3 mice were subjected to unilateral injection of hypertonic saline into a limbal vein, causing sclerosis of the o...

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Detalles Bibliográficos
Autores principales: Nettesheim, April, Dixon, Angela, Shim, Myoung Sup, Coyne, Aislyn, Walsh, Molly, Liton, Paloma B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Association for Research in Vision and Ophthalmology 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7441338/
https://www.ncbi.nlm.nih.gov/pubmed/32797200
http://dx.doi.org/10.1167/iovs.61.10.31