Cargando…
Autophagy in the Aging and Experimental Ocular Hypertensive Mouse Model
PURPOSE: To investigate autophagy in the outflow pathway and ganglion cell layer in the aging and ocular hypertensive mouse. METHODS: Both 4-month-old and 18-month-old C57BL/6J and GFP-LC3 mice were subjected to unilateral injection of hypertonic saline into a limbal vein, causing sclerosis of the o...
Autores principales: | Nettesheim, April, Dixon, Angela, Shim, Myoung Sup, Coyne, Aislyn, Walsh, Molly, Liton, Paloma B. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Association for Research in Vision and Ophthalmology
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7441338/ https://www.ncbi.nlm.nih.gov/pubmed/32797200 http://dx.doi.org/10.1167/iovs.61.10.31 |
Ejemplares similares
-
Autophagy deficiency protects against ocular hypertension and neurodegeneration in experimental and spontaneous glaucoma mouse models
por: Dixon, Angela, et al.
Publicado: (2023) -
Transcriptome analysis reveals autophagy as regulator of TGFβ/Smad-induced fibrogenesis in trabecular meshwork cells
por: Nettesheim, April, et al.
Publicado: (2019) -
Cathepsin B Localizes in the Caveolae and Participates in the Proteolytic Cascade in Trabecular Meshwork Cells. Potential New Drug Target for the Treatment of Glaucoma
por: Nettesheim, April, et al.
Publicado: (2020) -
Contribution of autophagy to ocular hypertension and neurodegeneration in the DBA/2J spontaneous glaucoma mouse model
por: Hirt, Joshua, et al.
Publicado: (2018) -
Evidence of Hypoxic Glial Cells in a Model of Ocular Hypertension
por: Jassim, Assraa H., et al.
Publicado: (2019)