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Increased Susceptibility to Glaucomatous Damage in Microfibril Deficient Mice

PURPOSE: To test whether mice with microfibril deficiency due to the Tsk mutation of fibrillin-1 (Fbn1(Tsk/+)) have increased susceptibility to pressure-induced retinal ganglion cell (RGC) degeneration. METHODS: Intraocular pressure (IOP) elevation was induced in Fbn1(Tsk/+) and wild type (wt) mice...

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Detalles Bibliográficos
Autores principales: Wu, Hang-Jing, Kuchtey, John, Kuchtey, Rachel W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Association for Research in Vision and Ophthalmology 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7441341/
https://www.ncbi.nlm.nih.gov/pubmed/32797197
http://dx.doi.org/10.1167/iovs.61.10.28