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Trehalose Induces Autophagy Against Inflammation by Activating TFEB Signaling Pathway in Human Corneal Epithelial Cells Exposed to Hyperosmotic Stress

PURPOSE: Autophagy plays an important role in balancing the inflammatory response to restore homeostasis. The aim of this study was to explore the mechanism by which trehalose suppresses inflammatory cytokines via autophagy activation in primary human corneal epithelial cells (HCECs) exposed to hype...

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Detalles Bibliográficos
Autores principales: Liu, Zhao, Chen, Ding, Chen, Xin, Bian, Fang, Qin, Wenjuan, Gao, Ning, Xiao, Yangyan, Li, Jinmiao, Pflugfelder, Stephen C., Li, De-Quan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Association for Research in Vision and Ophthalmology 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7441355/
https://www.ncbi.nlm.nih.gov/pubmed/32785678
http://dx.doi.org/10.1167/iovs.61.10.26