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Signaling Through the Erythropoietin Receptor Affects Angiogenesis in Retinovascular Disease

PURPOSE: Exogenous erythropoietin (EPO) is being considered for tissue protection and angiogenesis in retinal vascular diseases. However, studies are limited by insufficient tools to address signaling effects through the EPO receptor (EPOR). We used a humanized mouse model of hypoactive EPOR signali...

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Detalles Bibliográficos
Autores principales: Bretz, Colin A., Ramshekar, Aniket, Kunz, Eric, Wang, Haibo, Hartnett, M. Elizabeth
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Association for Research in Vision and Ophthalmology 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7441364/
https://www.ncbi.nlm.nih.gov/pubmed/32785675
http://dx.doi.org/10.1167/iovs.61.10.23