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A pan-cancer analysis of PBAF complex mutations and their association with immunotherapy response

There is conflicting data regarding the role of PBAF complex mutations and response to immune checkpoint blockade (ICB) therapy in clear cell renal cell carcinoma (ccRCC) and other solid tumors. We assess the prevalence of PBAF complex mutations from two large cohorts including the pan-cancer TCGA p...

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Detalles Bibliográficos
Autores principales: Hakimi, A. Ari, Attalla, Kyrollis, DiNatale, Renzo G., Ostrovnaya, Irina, Flynn, Jessica, Blum, Kyle A., Ged, Yasser, Hoen, Douglas, Kendall, Sviatoslav M., Reznik, Ed, Bowman, Anita, Hwee, Jason, Fong, Christopher J., Kuo, Fengshen, Voss, Martin H., Chan, Timothy A., Motzer, Robert J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7441387/
https://www.ncbi.nlm.nih.gov/pubmed/32820162
http://dx.doi.org/10.1038/s41467-020-17965-0