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Typically inhibiting USP14 promotes autophagy in M1-like macrophages and alleviates CLP-induced sepsis

Macrophages, with diverse functions and variable phenotypes, are considered as an important executor of inflammatory diseases. And it has been proved that autophagy is deeply connected with the development of inflammation, while the exact regulatory mechanism still remains unclear, and the applicati...

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Detalles Bibliográficos
Autores principales: Xu, Fang, Ma, Yuxiang, Huang, Wei, Gao, Jian, Guo, Mengmeng, Li, Jianxin, Kong, Lingdong, Liang, Guang, Du, Ronghui, Xu, Qiang, Wu, Xudong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7441392/
https://www.ncbi.nlm.nih.gov/pubmed/32820146
http://dx.doi.org/10.1038/s41419-020-02898-9