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Inhibition of inflammatory CCR2 signaling promotes aged muscle regeneration and strength recovery after injury

Muscle regeneration depends on a robust albeit transient inflammatory response. Persistent inflammation is a feature of age-related regenerative deficits, yet the underlying mechanisms are poorly understood. Here, we find inflammatory-related CC-chemokine-receptor 2 (Ccr2) expression in non-hematopo...

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Detalles Bibliográficos
Autores principales: Blanc, Roméo S., Kallenbach, Jacob G., Bachman, John F., Mitchell, Amanda, Paris, Nicole D., Chakkalakal, Joe V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7441393/
https://www.ncbi.nlm.nih.gov/pubmed/32820177
http://dx.doi.org/10.1038/s41467-020-17620-8