Cargando…
Inhibition of inflammatory CCR2 signaling promotes aged muscle regeneration and strength recovery after injury
Muscle regeneration depends on a robust albeit transient inflammatory response. Persistent inflammation is a feature of age-related regenerative deficits, yet the underlying mechanisms are poorly understood. Here, we find inflammatory-related CC-chemokine-receptor 2 (Ccr2) expression in non-hematopo...
Autores principales: | Blanc, Roméo S., Kallenbach, Jacob G., Bachman, John F., Mitchell, Amanda, Paris, Nicole D., Chakkalakal, Joe V. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7441393/ https://www.ncbi.nlm.nih.gov/pubmed/32820177 http://dx.doi.org/10.1038/s41467-020-17620-8 |
Ejemplares similares
-
Muscle‐specific functional deficits and lifelong fibrosis in response to paediatric radiotherapy and tumour elimination
por: Kallenbach, Jacob G., et al.
Publicado: (2022) -
Radiation-Induced Damage to Prepubertal Pax7+ Skeletal Muscle Stem Cells Drives Lifelong Deficits in Myofiber Size and Nuclear Number
por: Bachman, John F., et al.
Publicado: (2020) -
Chemoradiation impairs myofiber hypertrophic growth in a pediatric tumor model
por: Paris, Nicole D., et al.
Publicado: (2020) -
Prepubertal skeletal muscle growth requires Pax7-expressing satellite cell-derived myonuclear contribution
por: Bachman, John F., et al.
Publicado: (2018) -
Endurance exercise attenuates juvenile irradiation-induced skeletal muscle functional decline and mitochondrial stress
por: O’Connor, Thomas N., et al.
Publicado: (2022)