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Hippo/MST blocks breast cancer by downregulating WBP2 oncogene expression via miRNA processor Dicer

WBP2 transcription coactivator is an emerging oncoprotein and a key node of convergence between EGF and Wnt signaling pathways. Understanding how WBP2 is regulated has important implications for cancer therapy. WBP2 is tightly controlled by post-translational modifications, including phosphorylation...

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Detalles Bibliográficos
Autores principales: Lim, Shen Kiat, Tabatabaeian, Hossein, Lu, Ssu Yi, Kang, Shin-Ae, Sundaram, Gopinath Meenakshi, Sampath, Prabha, Chan, Siew Wee, Hong, Wan Jin, Lim, Yoon Pin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7441404/
https://www.ncbi.nlm.nih.gov/pubmed/32820148
http://dx.doi.org/10.1038/s41419-020-02901-3