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Glutamate Attenuates the Survival Property of IGFR through NR2B Containing N-Methyl-D-aspartate Receptors in Cortical Neurons

Glutamate-induced neurotoxicity is involved in various neuronal diseases, such as Alzheimer's disease. We have previously reported that glutamate attenuated the survival signaling of insulin-like growth factor-1 (IGF-1) by N-methyl-D-aspartate receptors (NMDARs) in cultured cortical neurons, wh...

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Detalles Bibliográficos
Autores principales: Zhao, Xia, Han, Chao, Zeng, Zhiwen, Liu, Linlin, Wang, Haitao, Xu, Jiangping, Feng, Zhong-Ping, Little, Peter J., Quirion, Remi, Zheng, Wenhua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7441446/
https://www.ncbi.nlm.nih.gov/pubmed/32849999
http://dx.doi.org/10.1155/2020/5173184