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Enhanced Expression of ABCB1 and Nrf2 in CD133-Positive Cancer Stem Cells Associates with Doxorubicin Resistance

The precise mechanism about drug resistance of cancer stem cells (CSCs) has not yet been completely understood. Based on the expression of CD44 and CD133, two well-recognized cell surface markers for CSC identification, we tried to separate HCT8 colorectal cancer cells into different subpopulations...

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Detalles Bibliográficos
Autores principales: Goto, Shinji, Kawabata, Tsuyoshi, Li, Tao-Sheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7441449/
https://www.ncbi.nlm.nih.gov/pubmed/32849878
http://dx.doi.org/10.1155/2020/8868849