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PGE(2) accounts for bidirectional changes in alveolar macrophage self-renewal with aging and smoking

Alveolar macrophages (AMs) are resident immune cells of the lung that are critical for host defense. AMs are capable of proliferative renewal, yet their numbers are known to decrease with aging and increase with cigarette smoking. The mechanism by which AM proliferation is physiologically restrained...

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Detalles Bibliográficos
Autores principales: Penke, Loka R, Speth, Jennifer M, Draijer, Christina, Zaslona, Zbigniew, Chen, Judy, Mancuso, Peter, Freeman, Christine M, Curtis, Jeffrey L, Goldstein, Daniel R, Peters-Golden, Marc
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Life Science Alliance LLC 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7441521/
https://www.ncbi.nlm.nih.gov/pubmed/32820026
http://dx.doi.org/10.26508/lsa.202000800