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PGE(2) accounts for bidirectional changes in alveolar macrophage self-renewal with aging and smoking
Alveolar macrophages (AMs) are resident immune cells of the lung that are critical for host defense. AMs are capable of proliferative renewal, yet their numbers are known to decrease with aging and increase with cigarette smoking. The mechanism by which AM proliferation is physiologically restrained...
Autores principales: | Penke, Loka R, Speth, Jennifer M, Draijer, Christina, Zaslona, Zbigniew, Chen, Judy, Mancuso, Peter, Freeman, Christine M, Curtis, Jeffrey L, Goldstein, Daniel R, Peters-Golden, Marc |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Life Science Alliance LLC
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7441521/ https://www.ncbi.nlm.nih.gov/pubmed/32820026 http://dx.doi.org/10.26508/lsa.202000800 |
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