The RECQL helicase prevents replication fork collapse during replication stress

Most tumors lack the G1/S phase checkpoint and are insensitive to antigrowth signals. Loss of G1/S control can severely perturb DNA replication as revealed by slow replication fork progression and frequent replication fork stalling. Cancer cells may thus rely on specific pathways that mitigate the d...

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Detalles Bibliográficos
Autores principales: Benedict, Bente, van Bueren, Marit AE, van Gemert, Frank PA, Lieftink, Cor, Guerrero Llobet, Sergi, van Vugt, Marcel ATM, Beijersbergen, Roderick L, te Riele, Hein
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Life Science Alliance LLC 2020
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7441523/
https://www.ncbi.nlm.nih.gov/pubmed/32820027
http://dx.doi.org/10.26508/lsa.202000668

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7441523/
https://www.ncbi.nlm.nih.gov/pubmed/32820027
http://dx.doi.org/10.26508/lsa.202000668

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