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Functional hyperemia drives fluid exchange in the paravascular space

The brain lacks a conventional lymphatic system to remove metabolic waste. It has been proposed that directional fluid movement through the arteriolar paravascular space (PVS) promotes metabolite clearance. We performed simulations to examine if arteriolar pulsations and dilations can drive directio...

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Detalles Bibliográficos
Autores principales: Kedarasetti, Ravi Teja, Turner, Kevin L., Echagarruga, Christina, Gluckman, Bruce J., Drew, Patrick J., Costanzo, Francesco
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7441569/
https://www.ncbi.nlm.nih.gov/pubmed/32819402
http://dx.doi.org/10.1186/s12987-020-00214-3