Cargando…
Development of Caco-2 cells expressing four CYPs via a mammalian artificial chromosome
BACKGROUND: Oral administration is the most common way to deliver drugs to the systemic circulation or target organs. Orally administered drugs are absorbed in the intestine and metabolized in the intestine and liver. In the early stages of drug development, it is important to predict first-pass met...
| Autores principales: | , , , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2020
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7441628/ https://www.ncbi.nlm.nih.gov/pubmed/32819341 http://dx.doi.org/10.1186/s12896-020-00637-8 |