The β-catenin/TCF-4 pathway regulates the expression of OPN in human osteoarthritic chondrocytes

BACKGROUND: Cartilage destruction is the main characteristic of osteoarthritis (OA), and osteopontin (OPN) is elevated in OA articular cartilage; however, the reason for the increased OPN level is not determined. In addition, Wnt/β-catenin signaling participates in the progression of OA. The aim of...

Descripción completa

Detalles Bibliográficos
Autores principales: Tian, Jian, Gao, Shu-Guang, Li, Yu-Sheng, Cheng, Chao, Deng, Zhen-Han, Luo, Wei, Zhang, Fang-Jie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7441722/
https://www.ncbi.nlm.nih.gov/pubmed/32819387
http://dx.doi.org/10.1186/s13018-020-01881-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7441722/
https://www.ncbi.nlm.nih.gov/pubmed/32819387
http://dx.doi.org/10.1186/s13018-020-01881-6

Ejemplares similares