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The β-catenin/TCF-4 pathway regulates the expression of OPN in human osteoarthritic chondrocytes

BACKGROUND: Cartilage destruction is the main characteristic of osteoarthritis (OA), and osteopontin (OPN) is elevated in OA articular cartilage; however, the reason for the increased OPN level is not determined. In addition, Wnt/β-catenin signaling participates in the progression of OA. The aim of...

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Detalles Bibliográficos
Autores principales:	Tian, Jian, Gao, Shu-Guang, Li, Yu-Sheng, Cheng, Chao, Deng, Zhen-Han, Luo, Wei, Zhang, Fang-Jie
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2020
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7441722/ https://www.ncbi.nlm.nih.gov/pubmed/32819387 http://dx.doi.org/10.1186/s13018-020-01881-6

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