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Inhibition of Rho kinase suppresses capsular contraction following lens injury in mice

PURPOSE: We investigated the effect of systemic fasudil hydrochloride and an inhibitor of nuclear translocation of myocardin-related transcription factor-A (MRTF-A) on capsular contraction in a puncture-injured lens in mice. MATERIALS AND METHODS: Lens injury of an anterior capsular break was achiev...

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Detalles Bibliográficos
Autores principales: Ichikawa, Kana, Tanaka, Sai-Ichi, Miyajima, Masayasu, Okada, Yuka, Saika, Shizuya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer - Medknow 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7442104/
https://www.ncbi.nlm.nih.gov/pubmed/32874837
http://dx.doi.org/10.4103/tjo.tjo_80_19