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DELTEX2 C-terminal domain recognizes and recruits ADP-ribosylated proteins for ubiquitination

Cross-talk between ubiquitination and ADP-ribosylation regulates spatiotemporal recruitment of key players in many signaling pathways. The DELTEX family ubiquitin ligases (DTX1 to DTX4 and DTX3L) are characterized by a RING domain followed by a C-terminal domain (DTC) of hitherto unknown function. H...

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Detalles Bibliográficos
Autores principales: Ahmed, Syed Feroj, Buetow, Lori, Gabrielsen, Mads, Lilla, Sergio, Chatrin, Chatrin, Sibbet, Gary J., Zanivan, Sara, Huang, Danny T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7442474/
https://www.ncbi.nlm.nih.gov/pubmed/32937373
http://dx.doi.org/10.1126/sciadv.abc0629