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TGF-β is insufficient to induce adipocyte state loss without concurrent PPARγ downregulation
Cell plasticity, the ability of differentiated cells to convert into other cell types, underlies the pathogenesis of many diseases including the transdifferentiation of adipocytes (fat cells) into myofibroblasts in the pathogenesis of dermal fibrosis. Loss of adipocyte identity is an early step in d...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7442643/ https://www.ncbi.nlm.nih.gov/pubmed/32826933 http://dx.doi.org/10.1038/s41598-020-71100-z |