A machine learning-based chemoproteomic approach to identify drug targets and binding sites in complex proteomes

Chemoproteomics is a key technology to characterize the mode of action of drugs, as it directly identifies the protein targets of bioactive compounds and aids in the development of optimized small-molecule compounds. Current approaches cannot identify the protein targets of a compound and also detec...

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Detalles Bibliográficos
Autores principales: Piazza, Ilaria, Beaton, Nigel, Bruderer, Roland, Knobloch, Thomas, Barbisan, Crystel, Chandat, Lucie, Sudau, Alexander, Siepe, Isabella, Rinner, Oliver, de Souza, Natalie, Picotti, Paola, Reiter, Lukas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7442650/
https://www.ncbi.nlm.nih.gov/pubmed/32826910
http://dx.doi.org/10.1038/s41467-020-18071-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7442650/
https://www.ncbi.nlm.nih.gov/pubmed/32826910
http://dx.doi.org/10.1038/s41467-020-18071-x

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