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Use of Paramagnetic (19)F NMR to Monitor Domain Movement in a Glutamate Transporter
In proteins where conformational changes are functionally important, the number of accessible states and their dynamics are often difficult to establish. Here we describe a novel (19)F-NMR spectroscopy approach to probe dynamics of large membrane proteins. We labeled a glutamate transporter homologu...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7442671/ https://www.ncbi.nlm.nih.gov/pubmed/32514183 http://dx.doi.org/10.1038/s41589-020-0561-6 |