The transcription factor Hhex cooperates with the corepressor Tle3 to promote memory B cell development

Memory B cells (MBCs) are essential for long-lived humoral immunity. However, the transcription factors involved in MBC differentiation are poorly defined. Here, by single-cell RNA-seq analysis, we identified a population of germinal center (GC) B cells in the process of differentiating into MBCs. U...

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Detalles Bibliográficos
Autores principales: Laidlaw, Brian J., Duan, Lihui, Xu, Ying, Vazquez, Sara E., Cyster, Jason G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7442689/
https://www.ncbi.nlm.nih.gov/pubmed/32601467
http://dx.doi.org/10.1038/s41590-020-0713-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7442689/
https://www.ncbi.nlm.nih.gov/pubmed/32601467
http://dx.doi.org/10.1038/s41590-020-0713-6

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