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The transcription factor Hhex cooperates with the corepressor Tle3 to promote memory B cell development
Memory B cells (MBCs) are essential for long-lived humoral immunity. However, the transcription factors involved in MBC differentiation are poorly defined. Here, by single-cell RNA-seq analysis, we identified a population of germinal center (GC) B cells in the process of differentiating into MBCs. U...
Autores principales: | Laidlaw, Brian J., Duan, Lihui, Xu, Ying, Vazquez, Sara E., Cyster, Jason G. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7442689/ https://www.ncbi.nlm.nih.gov/pubmed/32601467 http://dx.doi.org/10.1038/s41590-020-0713-6 |
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