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Structure of the ER membrane complex, a transmembrane-domain insertase
The ER membrane complex (EMC) cooperates with the Sec61 translocon to co-translationally insert a transmembrane helix (TMH) of many multi-pass integral membrane proteins into the ER membrane, and it is also responsible for inserting the TMH of some tail-anchored proteins (1–3). How EMC accomplishes...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7442705/ https://www.ncbi.nlm.nih.gov/pubmed/32494008 http://dx.doi.org/10.1038/s41586-020-2389-3 |