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Structure of the ER membrane complex, a transmembrane-domain insertase

The ER membrane complex (EMC) cooperates with the Sec61 translocon to co-translationally insert a transmembrane helix (TMH) of many multi-pass integral membrane proteins into the ER membrane, and it is also responsible for inserting the TMH of some tail-anchored proteins (1–3). How EMC accomplishes...

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Detalles Bibliográficos
Autores principales: Bai, Lin, You, Qinglong, Feng, Xiang, Kovach, Amanda, Li, Huilin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7442705/
https://www.ncbi.nlm.nih.gov/pubmed/32494008
http://dx.doi.org/10.1038/s41586-020-2389-3