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m(6)A-binding YTHDF proteins promote stress granule formation

Diverse RNAs and RNA-binding proteins form phase-separated, membraneless granules in cells under stress conditions. However, the role of the prevalent mRNA methylation, m(6)A, and its binding proteins in stress granule (SG) assembly remain unclear. Here, we show that m(6)A-modified mRNAs are enriche...

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Detalles Bibliográficos
Autores principales: Fu, Ye, Zhuang, Xiaowei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7442727/
https://www.ncbi.nlm.nih.gov/pubmed/32451507
http://dx.doi.org/10.1038/s41589-020-0524-y