Protein phosphatase 4 promotes Hedgehog signaling through dephosphorylation of Suppressor of fused

Reversible phosphorylation of Suppressor of fused (Sufu) is essential for Sonic Hedgehog (Shh) signal transduction. Sufu is stabilized under dual phosphorylation of protein kinase A (PKA) and glycogen synthase kinase 3β (GSK3β). Its phosphorylation is reduced with the activation of Shh signaling. Ho...

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Detalles Bibliográficos
Autores principales: Liao, Hengqing, Cai, Jing, Liu, Chen, Shen, Longyan, Pu, Xiaohong, Yao, Yixing, Han, Bo’ang, Yu, Tingting, Cheng, Steven Y., Yue, Shen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7442787/
https://www.ncbi.nlm.nih.gov/pubmed/32826873
http://dx.doi.org/10.1038/s41419-020-02843-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7442787/
https://www.ncbi.nlm.nih.gov/pubmed/32826873
http://dx.doi.org/10.1038/s41419-020-02843-w

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