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The mechanism of activation of the actin binding protein EHBP1 by Rab8 family members

EHBP1 is an adaptor protein that regulates vesicular trafficking by recruiting Rab8 family members and Eps15-homology domain-containing proteins 1/2 (EHD1/2). It also links endosomes to the actin cytoskeleton. However, the underlying molecular mechanism of activation of EHBP1 actin-binding activity...

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Detalles Bibliográficos
Autores principales: Rai, Amrita, Bleimling, Nathalie, Vetter, Ingrid R., Goody, Roger S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7442826/
https://www.ncbi.nlm.nih.gov/pubmed/32826901
http://dx.doi.org/10.1038/s41467-020-17792-3