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Machine learning for RNA sequencing-based intrinsic subtyping of breast cancer

Stratification of breast cancer (BC) into molecular subtypes by multigene expression assays is of demonstrated clinical utility. In principle, global RNA-sequencing (RNA-seq) should enable reconstructing existing transcriptional classifications of BC samples. Yet, it is not clear whether adaptation...

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Detalles Bibliográficos
Autores principales: Cascianelli, Silvia, Molineris, Ivan, Isella, Claudio, Masseroli, Marco, Medico, Enzo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7442834/
https://www.ncbi.nlm.nih.gov/pubmed/32826944
http://dx.doi.org/10.1038/s41598-020-70832-2