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DS-7080a, a Selective Anti-ROBO4 Antibody, Shows Anti-Angiogenic Efficacy with Distinctly Different Profiles from Anti-VEGF Agents

PURPOSE: Neovascular age-related macular degeneration (nAMD) results from choroidal neovascularization (CNV) and causes severe vision loss. Intravitreal anti-vascular endothelial growth factor (VEGF) therapies have significantly improved therapeutic outcomes; however, a substantial number of patient...

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Detalles Bibliográficos
Autores principales: Isumi, Yoshitaka, Hayashi, Shinko, Inoue, Tatsuya, Yoshigae, Yasushi, Sato, Toshiyuki, Hasegawa, Jun, Agatsuma, Toshinori
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Association for Research in Vision and Ophthalmology 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7442859/
https://www.ncbi.nlm.nih.gov/pubmed/32879763
http://dx.doi.org/10.1167/tvst.9.9.7