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DS-7080a, a Selective Anti-ROBO4 Antibody, Shows Anti-Angiogenic Efficacy with Distinctly Different Profiles from Anti-VEGF Agents
PURPOSE: Neovascular age-related macular degeneration (nAMD) results from choroidal neovascularization (CNV) and causes severe vision loss. Intravitreal anti-vascular endothelial growth factor (VEGF) therapies have significantly improved therapeutic outcomes; however, a substantial number of patient...
Autores principales: | Isumi, Yoshitaka, Hayashi, Shinko, Inoue, Tatsuya, Yoshigae, Yasushi, Sato, Toshiyuki, Hasegawa, Jun, Agatsuma, Toshinori |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Association for Research in Vision and Ophthalmology
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7442859/ https://www.ncbi.nlm.nih.gov/pubmed/32879763 http://dx.doi.org/10.1167/tvst.9.9.7 |
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