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Validating Fluorescent Chrnb4.EGFP Mouse Models for the Study of Cone Photoreceptor Degeneration

PURPOSE: To validate the application of a known transgenic mouse line with green fluorescent cones (Chrnb4.EGFP) to study cone photoreceptor biology and function in health and disease. METHODS: Chrnb4.EGFP retinas containing GFP(+) cones were compared with retinas without the GFP transgene via immun...

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Detalles Bibliográficos
Autores principales: Brunet, Alicia A., Fuller-Carter, Paula I., Miller, Annie L., Voigt, Valentina, Vasiliou, Sophia, Rashwan, Rabab, Hunt, David M., Carvalho, Livia S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Association for Research in Vision and Ophthalmology 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7442867/
https://www.ncbi.nlm.nih.gov/pubmed/32879784
http://dx.doi.org/10.1167/tvst.9.9.28