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Biochemical and functional characterization of a meiosis-specific Pch2/ORC AAA+ assembly

Pch2 is a meiosis-specific AAA+ protein that controls several important chromosomal processes. We previously demonstrated that Orc1, a subunit of the ORC, functionally interacts with budding yeast Pch2. The ORC (Orc1-6) AAA+ complex loads the AAA+ MCM helicase to origins of replication, but whether...

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Detalles Bibliográficos
Autores principales: Villar-Fernández, María Ascensión, Cardoso da Silva, Richard, Firlej, Magdalena, Pan, Dongqing, Weir, Elisabeth, Sarembe, Annika, Raina, Vivek B, Bange, Tanja, Weir, John R, Vader, Gerben
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Life Science Alliance LLC 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7442955/
https://www.ncbi.nlm.nih.gov/pubmed/32826290
http://dx.doi.org/10.26508/lsa.201900630