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Plasma membrane phosphatidylinositol (4,5)-bisphosphate promotes Weibel–Palade body exocytosis

Weibel–Palade bodies (WPB) are specialized secretory organelles of endothelial cells that control vascular hemostasis by regulated, Ca(2+)-dependent exocytosis of the coagulation-promoting von-Willebrand factor. Some proteins of the WPB docking and fusion machinery have been identified but a role of...

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Detalles Bibliográficos
Autores principales: Nguyen, Tu Thi Ngoc, Koerdt, Sophia N, Gerke, Volker
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Life Science Alliance LLC 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7442956/
https://www.ncbi.nlm.nih.gov/pubmed/32826291
http://dx.doi.org/10.26508/lsa.202000788