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Interleukin-6 Promotes Epithelial-Mesenchymal Transition and Cell Invasion through Integrin β6 Upregulation in Colorectal Cancer

The metastatic potential of colorectal cancer (CRC) is intensively promoted by the tumor microenvironment (TME) in a paracrine manner. As a pleiotropic inflammatory cytokine, Interleukin-6 (IL-6) is produced and involved in CRC, the same scenario where integrin αvβ6 also becomes upregulated. However...

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Detalles Bibliográficos
Autores principales: Sun, Qi, Shang, Yukui, Sun, Fengkai, Dong, Xiwen, Niu, Jun, Li, Fanni
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7443035/
https://www.ncbi.nlm.nih.gov/pubmed/32855767
http://dx.doi.org/10.1155/2020/8032187