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Interleukin-6 Promotes Epithelial-Mesenchymal Transition and Cell Invasion through Integrin β6 Upregulation in Colorectal Cancer
The metastatic potential of colorectal cancer (CRC) is intensively promoted by the tumor microenvironment (TME) in a paracrine manner. As a pleiotropic inflammatory cytokine, Interleukin-6 (IL-6) is produced and involved in CRC, the same scenario where integrin αvβ6 also becomes upregulated. However...
Autores principales: | Sun, Qi, Shang, Yukui, Sun, Fengkai, Dong, Xiwen, Niu, Jun, Li, Fanni |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7443035/ https://www.ncbi.nlm.nih.gov/pubmed/32855767 http://dx.doi.org/10.1155/2020/8032187 |
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