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Predicting Thioflavin Fluorescence of Retinal Amyloid Deposits Associated With Alzheimer's Disease from Their Polarimetric Properties

PURPOSE: To use machine learning in those with brain amyloid to predict thioflavin fluorescence (indicative of amyloid) of retinal deposits from their interactions with polarized light. METHODS: We imaged 933 retinal deposits in 28 subjects with post mortem evidence of brain amyloid using thioflavin...

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Detalles Bibliográficos
Autores principales: Qiu, Yunyi, Jin, Tao, Mason, Erik, Campbell, Melanie C. W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Association for Research in Vision and Ophthalmology 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7443113/
https://www.ncbi.nlm.nih.gov/pubmed/32879757
http://dx.doi.org/10.1167/tvst.9.2.47