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Risuteganib Protects against Hydroquinone–induced Injury in Human RPE Cells

PURPOSE: Cigarette smoking has been implicated in the pathogenesis of AMD. Integrin dysfunctions have been associated with AMD. Herein, we investigate the effect of risuteganib (RSG), an integrin regulator, on RPE cell injury induced by hydroquinone (HQ), an important oxidant in cigarette smoke. MET...

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Detalles Bibliográficos
Autores principales: Yang, Ping, Shao, Zixuan, Besley, Nicholas A., Neal, Samantha E., Buehne, Kristen L., Park, John, Karageozian, Hampar, Karageozian, Vicken, Ryde, Ian T., Meyer, Joel N., Jaffe, Glenn J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Association for Research in Vision and Ophthalmology 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7443126/
https://www.ncbi.nlm.nih.gov/pubmed/32818234
http://dx.doi.org/10.1167/iovs.61.10.35