Continuous bioactivity-dependent evolution of an antibiotic biosynthetic pathway

Antibiotic biosynthetic gene clusters (BGCs) produce bioactive metabolites that impart a fitness advantage to their producer, providing a mechanism for natural selection. This selection drives antibiotic evolution and adapts BGCs for expression in different organisms, potentially providing clues to...

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Detalles Bibliográficos
Autores principales: Johnston, Chad W., Badran, Ahmed H., Collins, James J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7443133/
https://www.ncbi.nlm.nih.gov/pubmed/32826900
http://dx.doi.org/10.1038/s41467-020-18018-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7443133/
https://www.ncbi.nlm.nih.gov/pubmed/32826900
http://dx.doi.org/10.1038/s41467-020-18018-2

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