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Continuous bioactivity-dependent evolution of an antibiotic biosynthetic pathway

Antibiotic biosynthetic gene clusters (BGCs) produce bioactive metabolites that impart a fitness advantage to their producer, providing a mechanism for natural selection. This selection drives antibiotic evolution and adapts BGCs for expression in different organisms, potentially providing clues to...

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Detalles Bibliográficos
Autores principales:	Johnston, Chad W., Badran, Ahmed H., Collins, James J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7443133/ https://www.ncbi.nlm.nih.gov/pubmed/32826900 http://dx.doi.org/10.1038/s41467-020-18018-2

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