Small molecules targeting RORγt inhibit autoimmune disease by suppressing Th17 cell differentiation

Th17 cells, a lymphocyte subpopulation that is characterized by the expression of the transcription factor “retinoic acid receptor-related orphan receptor gamma-t” (RORγt), plays an important role in the pathogenesis of autoimmune disease. The current study was set up to discover novel and non-stero...

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Detalles Bibliográficos
Autores principales: Tan, Jun, Liu, Huan, Huang, Minhao, Li, Na, Tang, Shibing, Meng, Jiayu, Tang, Shiyun, Zhou, Hongxiu, Kijlstra, Aize, Yang, Peizeng, Hou, Shengping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7443190/
https://www.ncbi.nlm.nih.gov/pubmed/32829384
http://dx.doi.org/10.1038/s41419-020-02891-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7443190/
https://www.ncbi.nlm.nih.gov/pubmed/32829384
http://dx.doi.org/10.1038/s41419-020-02891-2

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