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Transcriptomics Study to Determine the Molecular Mechanism by which sIL-13Rα2-Fc Inhibits Caudal Intervertebral Disc Degeneration in Rats

BACKGROUND: Intervertebral disc degeneration is related to tissue fibrosis. ADAMTS can degrade the important components of the ECM during the process of intervertebral disc degeneration, ultimately resulting in the loss of intervertebral disc function. sIL-13Rα2-Fc can inhibit fibrosis and slow down...

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Detalles Bibliográficos
Autores principales: Wang, Xin, Tan, Jianshi, Sun, Junhao, Fang, Pengzhong, Chen, Jinlei, Yuan, Wen, Chen, Huajiang, Liu, Yang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7443219/
https://www.ncbi.nlm.nih.gov/pubmed/32855969
http://dx.doi.org/10.1155/2020/7645989